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KMID : 0191120120270091109
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Journal of Korean Medical Science
2012 Volume.27 No. 9 p.1109 ~ p.1113
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A Case of Transient Central Diabetes Insipidus after Aorto-Coronary Bypass Operation
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Yu Chung-Hoon
Cho Jang-Hee
Jung Hee-Yeon
Lim Jeong-Hoon
Jin Mi-Kyung
Kwon Owen
Hong Kyung-Deuk
Choi Ji-Young
Yoon Se-Hee
Kim Chan-Duck
Kim Yong-Lim
Kim Gun-Jik
Park Sun-Hee
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Abstract
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Diabetes insipidus (DI) is characterized by excessive urination and thirst. This disease results from inadequate output of antidiuretic hormone (ADH) from the pituitary gland or the absence of the normal response to ADH in the kidney. We present a case of transient central DI in a patient who underwent a cardiopulmonary bypass (CPB) for coronary artery bypass grafting (CABG). A 44-yr-old male underwent a CABG operation. An hour after the operation, the patient developed polyuria and was diagnosed with central DI. The patient responded to desmopressin and completely recovered five days after surgery. It is probable that transient cerebral ischemia resulted in the dysfunction of osmotic receptors in the hypothalamus or hypothalamus-pituitary axis during CPB. It is also possible that cardiac standstill altered the left atrial non-osmotic receptor function and suppressed ADH release. Therefore, we suggest that central DI is a possible cause of polyuria after CPB.
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KEYWORD
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Polyuria, Central Diabetes Insipidus, Aorto-Coronary Bypass
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